

HUMAN CRYSTALLINE LENS
OVERVIEW:
The human lens has an elliptical, biconvex shape, measuring approximately 9.6mm in diameter and an axial length of 4mm

Comprised of: 64% water, 35% protein & 1% lipid
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Majority of this protein exists as a group of crystallins (α, β & γ)
Found between the iris and in front of the vitreous body
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It is suspended by the zonules of zinn
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These fibres contribute to accommodation - the ability to change the shape of the lens and focus light onto the retina, so objects can be viewed at different distances.
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During embryonic development, the adult lens is derived from surface ectoderm and grows throughout life by accumulation of new cells
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These cells occur near the lens equator, lengthening and pushing mature cells into the lens centre
With age, transparency deteriorates, causing increasing light scatter, colouration and decreasing elasticity