

FUTURE IOLS
SHAPE/ CURVATURE CHANGE DESIGNS
NuLens
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Influenced by the mechanism of an avian eye
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A highly muscular iris constriction causes bulging of the anterior lens surface
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Sulcus-based accommodating IOL
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The lens has a small chamber which houses silicone gel
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During accommodation:
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The gel is forced into the lens optic
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This causes a steepening effect on the anterior surface curvature
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Unique feature: it works as a reverse of normal crystalline lens accommodation:
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When focusing of near objects (accommodation), the ciliary muscle relaxes
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The reverse occurs for distance, where the ciliary muscle is contracted
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FluidVision
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PowerVision FluidVision IOL
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Acrylic IOL
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Hollow haptics and optics
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Connected to a central fluid cavity
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During accommodation:
- Zonular tension on the capsule decreases
- Reduction of the equatorial diameter of capsule
- This compresses the haptics, displacing fluid from the haptic into the optic
- Anterior surface curvature increases
- Therefore, a change in power is induced, causing a focus at near


LENS FILLING DESIGN
With IOL surgery, capsular opacification and leakage of silicone polymer have caused difficulties
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With a refilling lens, these problems can be minimised
Comprised of:
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An anterior foldable IOL with a posterior silicone IOL attached
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Which serves as both an optic and a plug for sealing the CCC.
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A transparent, liquid polymer is used to refill the lens, which lies between both IOLs
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This polymerises at body temperature when inserted into the eye.
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It enters via the small opening within the haptic of the silicone IOL
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Although many problems still remain with this technique, this method could help develop the IOL market further.
DYNAMIC CHANGE IN POWER DESIGNS
LiquiLens
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Contains two immiscible liquids
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Relies on the movement of liquid due to gravity during downward gaze
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The change in fluid in this direction alters the refractive index
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This in turn changes the focal length, to introduce new increase in power for near tasks
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However, intermediate vision is non-existent - works like a bifocal lens
ELECTRONIC IOL DESIGN
Sapphire AutoFocal (Elenza)
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First electronic IOL being developed
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Visual accommodation occurs as an ‘autofocus’ without the lens implant moving
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Distance and near focus automatically occurs as a result of individual pupillary responses
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Once implanted, the lens can be customised and programmed, adapting to the patient
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The fail-safe system means that if the IOL experiences a problem, the patient goes back to having distance vision only and has to wear reading glasses to correct for near
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The Elenza IOL electrically controls the refractive index of the liquid crystal which is inserted between a circular array of transparent electrodes.
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These diffractive crystal molecules are electroactivated to allow for near objects to be focused
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